Effect of switching time scale of receptor activity on chemotactic performance of Escherichia coli

In the chemotactic motion of Escherichia coli, switching transmembrane chemoreceptors between active and inactive states is one most important steps signaling pathway. We study effect this time-scale on performance cell. quantify by drift velocity Our extensive numerical simulations a detailed theoretical model show that as activity rate increases, increases then saturates. data also mean duration downhill run decreases strongly with rate, while an uphill relatively slowly. explain from temporal variation along trajectories. for large small rates nature qualitatively different behaviors but similar behavior run. This results in stronger dependence milder duration.